IU hasn't been to the NCAA Tournament in 13 years, so this idea seems far-fetched. That would be defending NCAA champion Fresno State, which was a #4 seed in its regional last year. IU is a very long shot, of course, and should be focused on nothing beyond the Louisville Cardinals. Nevertheless, the linked ESPN article does provide a reminder that the last two champions (Oregon State was a #3 seed in 2007) have come from the bottom half of the field.